MUMBAI, India, Aug. 17 -- Intellectual Property India has published a patent application (202641094627 A) filed by Dr. Ramya S; Aganmani S; Divyadharshini R; Ragul Amarnath M; and Sowmiya K on August 05, 2026, for Development Of A Polyphenol Nanogel-Cellulose Wound Dressing From Coconut Water And Pomegranate Peel.
Inventors include Dr. Ramya S; Aganmani S; Divyadharshini R; Ragul Amarnath M; and Sowmiya K.
The application for the patent was published on August 14, 2026, under issue no. 33/2026.
Abstract: Biocompatible and moisture-retentive scaffold, bacterial cellulose (BC), which is made from coconut water, is bioinert on its own and has no active antibacterial or antioxidant properties. Pomegranate peel, an agricultural by-product high in polyphenols like ellagic acid, has substantial anti-inflammatory, antibacterial, and antioxidant qualities. However, the instability and uncontrollable release of crude extracts limit its therapeutic usefulness. The goal of this effort is to overcome these individual constraints by combining both agro-wastes into a single bioactive composite dressing. Using a cellulose-producing bacterial culture, static fermentation of coconut water will yield bacterial cellulose, which will then be purified and dried. In order to improve the stability, solubility, and controlled release of the bioactive compounds in comparison to a raw extract, polyphenols from pomegranate peel will created by immersion loading the nanogel into the pure bacterial cellulose membrane with optional calcium chloride crosslinking. The produced material will be assessed using p1-l-dependent controlled-release studies, in vitro antioxidant and antibacterial assays, cell compatibility testing, and an in vivo wound-healing study evaluating tissue response and wound closure. This study intends to provide a biodegradable, affordable, and completely green bioactive dressing with improved wound-healing performance by combining the moisture-retentive scaffold qualities of bacterial cellulose with the antioxidant and antimicrobial activity of pomegranate polyphenols. This will provide a scalable substitute for synthetic dressings
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