MUMBAI, India, July 31 -- Intellectual Property India has published a patent application (202647087699 A) filed by Touchlight Ip Limited on July 17, 2026, for Duplexing Method.
Inventors include Rothwell, Paul James; Laura, Gemma Enrica Samiyah; Gazda, Livia Diana; and Kayyar, Bhavana.
The application for the patent was published on July 24, 2026, under issue no. 30/2026.
Abstract: The present invention relates to an improvement to cell-free, in vitro processes that involve the generation of single-stranded nucleic acid concatemers, where these concatemers favour folding into secondary structures due to the presence of stretches of self-complementary sequence. Single stranded concatemers may be produced via rolling circle amplification of a template nucleic acid under certain conditions. The self-annealing and folding of these single-stranded concatemers can frustrate the use of these concatemers for further isolation or product production, particularly where it is desired to make double stranded DNA. The present invention addresses this need by providing a simple and elegant way to ensure that the single stranded nucleic acid concatemer can effectively be duplexed, even if it forms complex self- annealed structures.
Disclaimer: Curated by HT Syndication.
