MUMBAI, India, June 30 -- Intellectual Property India has published a patent application (202421100979 A) filed by Enzene Biosciences Limited on December 19, 2024, for Green Solvent-Based Mixed-Solvent Strategy For The Synthesis Of Peptide.
Inventors include Kulkarni, Chandrakant; Dhote, Mohan; Pandit, Ravindra; Mathur, Abhishek; Dudhade, Rahul; and Khalde, Sagar.
The application for the patent was published on June 26, 2026, under issue no. 26/2026.
Abstract: The present invention relates to a mixed green solvent based process for the preparation of peptide. More specifically, the present invention relates to a process of the preparation of Octreotide using greener solvent. The process of present invention also focused on minimizing solvent consumption, especially DMF, trifluoroacetic acid (TFA) and ethers. The process of present invention also substitutes acetonitrile with methanol in the chromatographic purification steps. The process of present invention only addresses environmental concerns associated with DMF usage but also maintains the efficiency and effectiveness of the Octreotide synthesis process.
Disclaimer: Curated by HT Syndication.
