MUMBAI, India, Aug. 17 -- Intellectual Property India has published a patent application (202617056339 A) filed by Nanovation Therapeutics Inc. on May 04, 2026, for Haematopoietic Stem And/Or Progenitor Cell Delivery Method And Compositions For Use Thereof.
Inventors include Silva, Jessica A. F. D.; Kurek, Daniel; and Kulkarni, Jayesh.
The application for the patent was published on August 14, 2026, under issue no. 33/2026.
Abstract: The present disclosure provides a method for delivery of cargo to a haematopoietic stem or progenitor cell of a subject, the method comprising contacting a lipid nanoparticle encapsulating the cargo with the haematopoietic stem or progenitor cell ex vivo or in vivo, thereby causing cellular uptake of the cargo, the lipid nanoparticle having between 30 mol% and 70 mol% of a neutral or zwitterionic amphipathic lipid having a net-neutral charge at physiological pH, an ionizable cationic lipid, and a sterol, wherein the lipid nanoparticle is substantially uncharged at physiological pH and has an apparent pKa of between 6.0 and 7.5. Further provided are lipid nanoparticle compositions and uses thereof.
Disclaimer: Curated by HT Syndication.
