MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202641123795 A) filed by Vellore Institute Of Technology on October 15, 2026, for History-Aware Pharmaceutical Stability State Reconstruction And Last-Safe Intervention Prediction System.

Inventors include Rajkumar Rajasekaran; and C. Mirthunjay Sekar.

The application for the patent was published on October 23, 2026, under issue no. 43/2026.

Abstract: ABSTRACT HISTORY-AWARE PHARMACEUTICAL STABILITY STATE RECONSTRUCTION AND LAST-SAFE INTERVENTION PREDICTION SYSTEM A pharmaceutical stability intelligence system includes a data acquisition unit (110) acquiring a recorded environmental exposure history of a pharmaceutical product in a pharmaceutical container (10), and a processing unit (120). An event sequencing module (124) organizes the history into an ordered stress-recovery sequence. A stability state propagation module (126) iteratively propagates a quality attribute to obtain a current product state, which is projected and compared with an acceptability threshold. A degradation debt module (128) separates accumulated degradation into an irreversible degradation debt component and a recoverable residual degradation component, and a future stress susceptibility is derived from stress-event position and recovery periods. A recoverability state and boundary module (134) determines a recoverability state and a recoverability boundary distinct from the threshold. An intervention and timing module (140) outputs a corrective intervention and latest application time within a last-safe intervention window, applied through storage and handling equipment (180). (Fig. 1)

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