MUMBAI, India, Aug. 10 -- Intellectual Property India has published a patent application (202541007193 A) filed by Granules India Limited on January 29, 2025, for Improved Process For The Preparation Of 2-Bromo-1-(3-Chlorophenyl)-1-Propanone And It’s Use In The Preparation Of Bupropion.

Inventors include Pullela Venkata Srinivas; Sampath Kumar Upparapalli; and Shreyas Satish Kulkarni.

The application for the patent was published on July 31, 2026, under issue no. 31/2026.

Abstract: ABSTRACT IMPROVED PROCESS FOR THE PREPARATION OF 2-BROMO-1-(3-CHLOROPHENYL)-1-PROPANONE AND IT’S USE IN THE PREPARATION OF BUPROPION: The present invention relates to an improved process for the preparation of 2-Bromo-1-(3-chlorophenyl)-1-propanone. The present invention specifically relates to an improved process for the preparation of 2-Bromo-1-(3-chlorophenyl)-1-propanone by using 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) as a brominating reagent and its further conversion to Bupropion or its pharmaceutically acceptable salts. 2-Bromo-1-(3-chlorophenyl)-1-propanone. Dated this: 27th day of January, 2026. Signature: Name: Mr. Rama Rao Javvaji Patent Agent Reg. No.: IN/PA-1669 GRANULES INDIA LIMITED 15th Floor, Granules Tower, Botanical Garden Road, Kondapur, Hyderabad, Telangana, India- 500 084

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