MUMBAI, India, June 26 -- Intellectual Property India has published a patent application (202617017583 A) filed by Phoenix Biosciences Sa on February 17, 2026, for Improved Reaction Mixture For In Vitro Messenger Ribonucleic Acid Transcription.

Inventors include Kallel, Hla; Laterre, Raphaelle; and Vannoorenberghe, Remy.

The application for the patent was published on June 19, 2026, under issue no. 25/2026.

Abstract: The current invention relates to a reaction mixture for in vitro messenger ribonucleic acid (mRNA) transcription comprising: ribonucleotide triphosphates (rNTPs) comprising adenosine triphosphates (ATPs), cytidine triphosphates (CTPs), uridine triphosphates (UTPs), guanosine triphosphates (GTPs), an RNA polymerase and magnesium (Mg2+), wherein a molar concentration of the magnesium in said reaction mixture is at least above about 35 mM and lower or equal to about 50 mM. The invention further relates to use of said reaction mixture, a method for producing a mRNA by incubating a DNA template in said reaction mixture and a kit comprising said reaction mixture.

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