MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202641123626 A) filed by Ms. Sathiyapriya P; and Dr. Dhivya. L. S on October 15, 2026, for Integrated Phytochemical, Biological, Analytical And In Silico Evaluation Of Bryophyllum Pinnatum For Identification Of Potential Anticancer Phytoconstituents.
Inventors include Ms. Sathiyapriya P; and Dr. Dhivya. L. S.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: The present invention relates to an integrated experimental and computational process for prioritizing phytoconstituents from Bryophyllum pinnatum for anticancer research. Authenticated leaves are processed and separately extracted using n-hexane, ethanol, hydroalcoholic solvent and water. The extracts undergo physicochemical evaluation, qualitative phytochemical screening and comparative in vitro antioxidant, nitric oxide-scavenging, antibacterial and protein-denaturation assays. A hydroalcoholic extract is selected on the basis of the combined results and characterized by Fourier-transform infrared spectroscopy and X-ray diffraction. Constituent- identification information, including gas chromatography–mass spectrometry data where applicable, supports candidate selection. Selected phytoconstituents are computationally assessed for absorption, distribution, metabolism, excretion and toxicity characteristics and subjected to molecular docking against cancer-associated protein targets. The integrated process enables systematic prioritization of candidates for subsequent experimental validation without establishing clinical anticancer efficacy. Accompanied Drawing [FIGS. 1-2].
Disclaimer: Curated by HT Syndication.
