MUMBAI, India, June 24 -- Intellectual Property India has published a patent application (202617065172 A) filed by Ventus Therapeutics U. S. , Inc. on May 23, 2026, for Lactam Derivatives For Inhibiting Nlrp3 And Uses Thereof.
Inventors include Dorich, Stphane; and Ciblat, Stphane.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: The present disclosure relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R3, R4, R4a, R4b, Z, R5, R6, R6', and R6", are described herein, and R7 and R2 are joined to form a 5- to 10-membered monocyclic or bicyclic heterocyclyl or 5- to 10-membered monocyclic or bicyclic heteroaryl, and methods of preparation, methods of treatment and prevention, and pharmaceutical compositions comprising same. The present disclosure further relates to the use of the compounds of Formula (I), and pharmaceutically acceptable salts thereof, in the treatment or prevention of NLRP3-related diseases and disorders.
Disclaimer: Curated by HT Syndication.
