MUMBAI, India, June 24 -- Intellectual Property India has published a patent application (202617063330 A) filed by Seoul National University R&db Foundation on May 19, 2026, for Method For Designing Wide Range Of Rna Modification Library Including All Surrounding Sequences Of Rna Modification And Use Thereof.
Inventors include Baek, Daehyun; Kang, Gihyeon; Chang, Hee Ryung; Choi, Heejin; and Hwang, Hyeonseo.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: The present invention relates to a method for designing a wide range of RNA modification libraries including all surrounding sequences of RNA modification and a use thereof. The present invention can construct a modified RNA library by introducing various types of RNA modifications and can reflect all possible combinations of surrounding sequences on both sides of the modified RNA library, thereby differing from the previously reported modified RNA library construction method. In addition, when single-molecule RNA sequencing is performed using a modified RNA library according to the present invention, a high-quality reference data set including all combinatorially possible motifs can be generated. Using this dataset as training data for deep learning (or machine learning) makes it possible not only to develop new RNA modification detection software with higher accuracy, but also to simultaneously detect multiple RNA modifications in a single analysis, beyond the limitations of existing software, which are often restricted within specific RNA modifications or exhibit reduced prediction accuracy for other modifications.
Disclaimer: Curated by HT Syndication.
