MUMBAI, India, Aug. 12 -- Intellectual Property India has published a patent application (202541009745 A) filed by Yenepoya Deemed To Be University on February 06, 2025, for Method For Identification Of Oncogenic Peptide From Enterococcus Hirae Associated With Colon Cancer.
Inventors include Dr. Rajesh P Shastry; Dr. Asif Hameed; Dr. Keshava Prasad Thottethodi Subrahmanya; and Dr. Ashwini Prabhu.
The application for the patent was published on August 07, 2026, under issue no. 32/2026.
Abstract: ABSTRACT METHOD FOR IDENTIFICATION OF ONCOGENIC PEPTIDE FROM ENTEROCOCCUS HIRAE ASSOCIATED WITH COLON CANCER The present disclosure relates to a method for the identification of an oncogenic peptide from a gut bacterial isolate associated with colon cancer. More particularly, the oncogenic peptide is identified from Enterococcus hirae, isolated from the faecal samples of a colon cancer subject. The disclosed method comprises steps of: identifying an oncogenic gut bacterial isolate, wherein the gut bacterial isolate is Enterococcus hirae; obtaining cell-free supernatant (CFS) from Enterococcus hirae; desalting; eluting peptides and subjecting to Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) through Data-Dependent Acquisition (DDA); and identifying oncogenic peptides. The identified oncogenic peptide(s) could serve as diagnostic biomarkers for detecting gut bacteria-linked colon cancer types.
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