MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202418050721 A) filed by Escient Pharmaceuticals, Inc. on July 02, 2024, for Modulators Of Mas-Related G-Protein Receptor X4 And Related Products And Methods.

Inventors include Yeager, Adam; Selfridge, Brandon; Sainz, Marcos; Martinborough, Esther; Boehm, Marcus; and Huang, Liming.

The application for the patent was published on July 10, 2026, under issue no. 28/2026.

Abstract: Methods are provided for modulating MRGPR X4 generally, or for treating a MRGPR X4 dependent condition more specifically, by contacting the MRGPR X4 or administering to a subject in need thereof, respectively, an effective amount of a compound having the structure of Formula (I): (I) 10 or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein n, x, A, Q1, Q2, Z, R, R1 , R 2 ,R3 , R4 and R5 are as defined herein. Pharmaceutical compositions containing such compounds, as well as to compounds themselves, are also provided.

Disclaimer: Curated by HT Syndication.