MUMBAI, India, June 24 -- Intellectual Property India has published a patent application (202618061441 A) filed by Sanofi on May 14, 2026, for Monoclonal Antibodies Binding To Chikv.
Inventors include Carter, Kara; Lemoine, Cendrine; Mandron, Marie; Park, Sunghae; Qiu, Huawei; and Rothblatt, Jonathan.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: An isolated monoclonal antibody binding to CHIKV comprising three CDRHs and three CDRLs, wherein (i) said CDRHs have amino acid sequences of SEQ ID NO: 11, 12 and 13, and said CDRLs have amino acid sequences of SEQ ID NO: 14, GTS and 16, wherein said antibody further comprises an Fc region comprising at least one residue selected from (a) a leucine at position 428 and a serine at position 434 or (b) a tyrosine at position 252, a threonine at position 254 and a glutamic acid at position 256, respectively or (ii) said CDRHs have amino acid sequences of SEQ ID NO: 11, 12 and 33, except that the amino acid at position 8 of SEQ ID NO: 33 is I, or the amino acid at position 12 of SEQ ID NO: 33 is Q; or the amino acid at position 13 of SEQ ID NO: 33 is A, and said CDRLs have amino acid sequences of SEQ ID NO: 14, GTS and 16, and wherein said antibody further optionally comprises an Fc region comprising at least one residue selected from (a) a leucine at position 428 and a serine at position 434, respectively or (b) a tyrosine at position 252, a threonine at position 254 and a glutamic acid at position 256, respectively.
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