MUMBAI, India, July 7 -- Intellectual Property India has published a patent application (202617070175 A) filed by The Children'S Hospital Of Philadelphia on June 04, 2026, for Norepinephrine Transporter-Targeted Prodrugs For Cancer Therapy.
Inventors include Chorny, Michael; Alferiev, Ivan; and Brodeur, Garrett, M..
The application for the patent was published on July 03, 2026, under issue no. 27/2026.
Abstract: Provided are macromolecular prodrugs in which 7-hydroxymethylcamptothecin (CPT-MeOH) is covalently bonded to a polymer via ester bonds that are labile under physiological conditions. The CPT-MeOH may be functionalized with a norepinephrine transporter (NET) ligand. Also provided are methods of treating cancer, especially neuroblastoma with the macromolecular prodrugs.
Disclaimer: Curated by HT Syndication.
