MUMBAI, India, Aug. 12 -- Intellectual Property India has published a patent application (202631062222 A) filed by Ved Prakash Verma; and Dr. Priyanka Yadav on May 16, 2026, for Novel Isatin-Based Hydrazone Derivatives Of N-Amino-11-Azaartemisinin And Their Composition As Antimalarial Agents.
Inventors include Ved Prakash Verma; Dr. Priyanka Yadav; Komal Rathi; Dinesh Kumar Yadav; Aman Bhardwaj; and Ashwani Kumar.
The application for the patent was published on August 07, 2026, under issue no. 32/2026.
Abstract: The present invention discloses novel isatin-derived hydrazone analogues of N-amino-11-azaartemisinin represented by formula I, and there compositions thereof as antimalarial agent. wherein, R is (a) 5-fluoroisatin, 7-fluoroisatin, 5-chloroisatin, 6-chloroisatin, 7-chloroisatin, 5-bromoisatin, 6-bromoisatin, 7-bromoisatin, 5- iodoisatin, 5-methylisatin, 5-nitroisatin, 5-methoxyisatin, 6-methoxyisatin, N-benzylated with aryl moiety selected from -benzyl; (b) 7-fluoroisatin, 6-chloroisatin, 5- iodoisatin, 5-methoxyisatin N-benzylated with aryl moiety selected from -methylnaphthalene; (c) 6-chloroisatin, 5-iodoisatin, 5-methoxyisatin N-benzylated with aryl moiety selected from -4-chlorophenyl; (d) 7-fluoroisatin, 6-chloroisatin, 5-iodoisatin, 5-methoxyisatin N-benzylated with aryl moiety selected from -3-chlorophenyl; (e) 6-chloroisatin, 5-iodoisatin, 5-methoxyisatin N-benzylated with aryl moiety selected from -methylbiphenyl; wherein substitution is with one or more moieties selected from but not limited to halogen, amino, nitro, cyano, hydroxy, alkoxy, thio, alkylthio group.
Disclaimer: Curated by HT Syndication.
