MUMBAI, India, Aug. 17 -- Intellectual Property India has published a patent application (202421073168 A) filed by Micro Crispr Pvt. Ltd. on September 27, 2024, for Recombinant Constructs, Vectors And Cells For Expressing Chimeric Antigen Receptors, And Methods Thereof.

Inventors include Gupta, Paridhi; and Bilakhia, Aaman Anjum.

The application for the patent was published on August 14, 2026, under issue no. 33/2026.

Abstract: ABSTRACT RECOMBINANT CONSTRUCTS, VECTORS AND CELLS FOR EXPRESSING CHIMERIC ANTIGEN RECEPTORS, AND METHODS THEREOF The present invention relates to recombinant constructs encoding chimeric antigen 5 receptors and neutralizing antigen-binding fragments, vectors, engineered chimeric antigen receptors T-cells (CAR-T), and methods for expressing chimeric antigen receptors and neutralizing antigen-binding fragment. The present invention also relates to compositions and methods for enhancing and maintaining chimeric antigen receptor expressing T cells, while reducing cytotoxic effects of CAR-T cell therapies.

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