MUMBAI, India, July 24 -- Intellectual Property India has published a patent application (202418060961 A) filed by Meiragtx Uk Ii Limited on August 12, 2024, for Regulation Of Gene Expression Via Aptamer-Mediated Control Of Self- Cleaving Ribozymes.
Inventors include Volles, Michael, J.; Danos, Olivier, F.; Boyne, Alex, R.; Zennou, Veronique; and Guo, Xuecui.
The application for the patent was published on July 17, 2026, under issue no. 29/2026.
Abstract: The invention provides polynucleotide constructs for the regulation of gene expression by aptamer-based modulation of self-cleaving ribozymes and methods of using the constructs to regulate gene expression in response to the presence or absence of a ligand that binds the aptamer. The invention further provides methods for making and using riboswitches that decrease target gene expression in response to an aptamer ligand as well as riboswitches that increase target gene expression in response to an aptamer ligand.
Disclaimer: Curated by HT Syndication.
