MUMBAI, India, Oct. 26 -- Intellectual Property India has published a patent application (202541037489 A) filed by Rajiv Gandhi Centre For Biotechnology on April 17, 2025, for Screening Methods For Cancers Using Pir-019324 As A Biomarker.
Inventors include Dr. Ani V Das; Ms. Midhunaraj K; Ms. Mary Angelin; Dr. Lakshmi S; and Mr. Arun Warrier.
The application for the patent was published on October 23, 2026, under issue no. 43/2026.
Abstract: ABSTRACT A KIT AND METHOD FOR DETECTION OF piR-019324 AS A BIOMARKER The present invention relates to a system for detection of a piRNA biomarker, piR-019324, in biological samples. The invention provides a kit comprising an RNA isolation module, a polyadenylation module, a reverse transcription module, and a quantitative PCR module including oligonucleotide primers specific to piR-019324. The kit may further include an endogenous control and defined reagent compositions for RNA processing and amplification. The invention further provides an oligonucleotide complementary to piR-019324 comprising a defined nucleotide sequence and optional chemical modifications. A method for detecting piR-019324 is also disclosed, comprising RNA isolation, small RNA extraction, polyadenylation, cDNA synthesis, and amplification using specific primers. The system enables detection of piR-019324 in biological samples including blood, plasma, serum, and urine. The invention further identifies piR-019324 as a biomarker associated with cervical cancer, exhibiting elevated expression and early detectability. [Figure 2]
Disclaimer: Curated by HT Syndication.
