MUMBAI, India, Aug. 10 -- Intellectual Property India has published a patent application (202411104065 A) filed by Lovely Professional University on December 28, 2024, for Selective Serotonin Blockers For Cognitive Dysfunction Treatment.

Inventor includes Dr. Rakesh Kumar.

The application for the patent was published on July 31, 2026, under issue no. 31/2026.

Abstract: The present invention relates to a pharmaceutical composition and method for treating cognitive dysfunction, particularly in patients with neurodegenerative diseases such as Alzheimer's and Parkinson's, as well as mental health disorders including schizophrenia and depression. The composition comprises a selective serotonin blocker targeting 5-HT2A and 5-HT6 receptors, combined with a pharmaceutically acceptable carrier. This selective serotonin blocker is configured to modulate serotonin signaling in the brain, thereby regulating neurotransmitters such as dopamine and glutamate, which are crucial for cognitive function. The invention further includes a method of administration in controlled dosage forms, such as tablets and injections, to optimize therapeutic efficacy while minimizing side effects commonly associated with serotonin reuptake inhibitors, such as emotional blunting or sexual dysfunction. The selective serotonin blocker may include 5-HT6 receptor antagonists like idalopirdine and 5-HT2A receptor antagonists found in atypical antipsychotics, providing a targeted approach to cognitive dysfunction treatment.

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