MUMBAI, India, June 24 -- Intellectual Property India has published a patent application (202617063304 A) filed by Merck Sharp & Dohme LLC on May 19, 2026, for Small Molecule Inhibitors Of Kras Proteins.
Inventors include Kawamura, Shuhei; Kobayakawa, Yu; Oshima, Tsuyoshi; Uno, Takao; and Schpf, Patrick.
The application for the patent was published on June 12, 2026, under issue no. 24/2026.
Abstract: Compounds of Formulae (I)-(VII) or their pharmaceutically acceptable salts can inhibit the G12C, G12D, G12V, and/or G13D mutants of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds of Formulae (I)-(VII) or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.
Disclaimer: Curated by HT Syndication.
