MUMBAI, India, June 26 -- Intellectual Property India has published a patent application (202641052244 A) filed by Prasad V. Potluri Siddhartha Institute Of Technology on April 24, 2026, for Smart Stimuli-Responsive Biofabricated Ruthenium Oxide Nanoparticle Delivery System For Targeted Skin Cancer Therapy.

Inventors include Dr. N. Usha Rani; Dr. K. Ramanjaneyulu; Dr. P. T. S. R. K. Prasada Rao; K. Hemanth; and K. Snehith.

The application for the patent was published on June 19, 2026, under issue no. 25/2026.

Abstract: Abstract: The present invention relates to a smart nanoparticle-based delivery system for targeted cancer therapy. The system utilizes biofabricated Ruthenium Oxide Nanoparticles synthesized using plant extracts of Causonis trifolia and incorporates a stimuli-responsive coating that activates under tumor-specific conditions such as acidic pH and elevated reactive oxygen species. The invention enables controlled release of therapeutic agents and selective cytotoxic activity, thereby enhancing treatment efficacy while minimizing side effects. The system offers a sustainable, biocompatible, and efficient approach for targeted skin cancer therapy. 7. Key Words: Ruthenium Oxide Nanoparticles, Causonis trifolia, Biofabrication, Targeted Drug Delivery, Skin Cancer, Stimuli-Responsive System, Reactive Oxygen Species, Nanomedicine, Smart Nanocarriers, Green Synthesis

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