MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202648024858 A) filed by Novozymes As on March 02, 2026, for Stabilized Subtilisin Composition.
Inventors include Mikkelsen, Lise Munch; Ponzini, Francesco; Bisaccia, Roberto; and Canevotti, Renato Number.
The application for the patent was published on July 10, 2026, under issue no. 28/2026.
Abstract: STABILIZED SUBTILISIN COMPOSITION ABSTRACT The conversion of a peptide aldehyde to a hydrosulfite adduct can be used to increase the aqueous solubility in the purification of the peptide aldehydes. Advantageously, this hydrosulfite adduct is itself effective as a subtilisin inhibitor and stabilizer and it can also stabilize a second enzyme if present. The hydrosulfite adduct is effective as a subtilisin inhibitor, and it maintains its inhibitory and stabilizing effect in a liquid detergent during storage. Thus, use of the hydrosulfite adduct can avoid the cost and time of converting it back to the peptide aldehyde and subsequent drying of the peptide aldehyde can be saved, and this can avoid the inconvenience of handling the peptide aldehyde in powder form or as a highly diluted aqueous solution
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