MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202621060554 A) filed by Sage University on May 12, 2026, for System And Method For Electrochemical Detection Of Controlled Substances In Biological Fluids.
Inventors include Dr. Prashant Jain; Ms. Sakshi Agrawal; Surbhi Sudame; Dr. Kalpana Dongre; Ashu Dhakad; and Rashi Bhatt.
The application for the patent was published on July 10, 2026, under issue no. 28/2026.
Abstract: ABSTRACT The present disclosure relates to electrochemical detection of controlled substances in biological fluids. The system (100) includes a potentiostat circuit (104) that applies a square wave voltammetric waveform to a plurality of working electrodes (106), each functionalized with nucleic acid aptamer molecules specific to a target controlled substance class and incorporating a redox-active label. A hardware processor (102) receives electrical current measurements from the working electrodes (106) during forward and reverse waveform phases, computing differential current values at each potential step to generate a voltammogram. The differential approach rejects capacitive charging currents arising from the biological matrix. The hardware processor (102) identifies peak current magnitudes from the voltammogram, compares them against pre-stored calibration data, and determines controlled substance concentrations. From a single biological fluid sample application, the system (100) concurrently determines concentrations across all working electrodes (106), enabling simultaneous multi-substance detection with enhanced selectivity and sensitivity. FIG. 1
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