MUMBAI, India, Oct. 5 -- Intellectual Property India has published a patent application (202521029943 A) filed by Tata Consultancy Services Limited on March 28, 2025, for Systems And Methods For Predicting Immunogenic Epitopes From Antigen Protein Sequences.
Inventors include Rana, Sadhna; Sajeed, Rakshanda; Pradhan, Swatantra; and Srinivasan, Rajgopal.
The application for the patent was published on October 02, 2026, under issue no. 40/2026.
Abstract: ABSTRACT SYSTEMS AND METHODS FOR PREDICTING IMMUNOGENIC EPITOPES FROM ANTIGEN PROTEIN SEQUENCES Epitopes identification is a very important problem and has implications in designing vaccines for emerging viruses, bacteria and fight antimicrobial resistance. Traditional methods of epitope mapping are costly, and time consuming. Present disclosure provides a system and a method that processes structural features along with the features from protein language models and apply deep concatenation techniques to combine the features for obtaining a concatenated feature set. A weight for each feature amongst the concatenated features set and a bias for the concatenated features set are learnt to obtain an optimal combination of features set based on which amino acid residues are predicted as one of an epitope or a non-epitope. Further, epitopes are prioritized using a plurality of attention scores capturing a T-B association by using a protein language model, to obtain a set of immunogenic B-cell epitopes. [
Disclaimer: Curated by HT Syndication.
